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Universitas Hasanuddin
Research output:Contribution to journalArticlepeer-review

Unveiling the prognostic potential of mayo cardiac intensive care unit admission risk score and pneumonia severity index in community-acquired pneumonia patients admitted to the intensive cardiovascular care unit

Wijaya H.S.

Gazzetta Medica Italiana Archivio Per Le Scienze Mediche

Q4
Published: 2025

Abstract

BACKGROUND: Pneumonia, a prevalent comorbidity, increases mortality risk in cardiovascular disease patients. Prediction scoring systems such as M-CARS and PSI assist in treatment decisions and mortality predictions. This study compares M-CARS and PSI in predicting 30-day mortality among ICCU patients with comorbid CAP.METHODS: This 6-month prospective cohort study recruited all ICCU patients at Dr. Wahidin Sudirohusodo Hospital with comorbid CAP. Within the first 24 hours of admission, patients underwent scoring using M-CARS and PSI, which were then recorded. Patients were monitored for mortality over a 30-day follow-up period. The study subsequently compared the accuracy of M-CARS and PSI using receiver operating characteristic (ROC) curves.RESULTS: Out of the 51 patients, the majority were male (37, 72.5%), with a mean age of 58.1 ± 12.7 years. Most of our patients presented with acute coronary syndrome (74.5%). The study findings indicated that both scoring systems exhibit good accuracy based on the ROC curve analysis. M-CARS achieved an AUC of 0.717 (P=0.018), while PSI demonstrated a higher AUC of 0.915 (P<0.001). Using a cut-off of 1.5, M-CARS showed a sensitivity of 64.3% and specificity of 78.4% for predicting 30-day mortality, whereas PSI, with a cut-off of 105, demonstrated a sensitivity of 92.9% and specificity of 78%.CONCLUSIONS: The PSI and M-CARS scores exhibit similar specificity, but the PSI score demonstrates superior sensitivity compared to M-CARS. M-CARS is easier to utilize and demonstrates considerable accuracy in predicting 30-day mortality among ICCU patients with comorbid CAP.

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MedicineSciences
Receiver operating characteristicSciences
PneumoniaSciences
Intensive care unitSciences
Internal medicineSciences
Pneumonia severity indexSciences
Prospective cohort studySciences
Coronary care unitSciences
Acute coronary syndromeSciences
CohortSciences
Emergency medicineSciences
Framingham Risk ScoreSciences
Risk of mortalitySciences
Cohort studySciences
Intensive care medicineSciences
Area under the curveSciences
Scoring systemSciences
Risk assessmentSciences
Severity of illnessSciences
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Prognostic modelSciences
Predictive value of testsSciences
Area under curveSciences
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Youden's J statisticSciences
Intensive careSciences
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PediatricsSciences
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Mortality rateSciences