The use of cysteamine as a hyperpigmentation brightening agent in Indonesian women

Abstract

There are many depigmenting preparations available on the cosmetic market, which often cause side effects such as dry skin, flaking, redness or burning. Intensive research is being conducted on substances with comparable efficacy but a better tolerability profile. One such substance is cysteamine. This study aimed to evaluate the effectiveness of combining 2.5% cysteamine with 2% Galactomyces ferment filtrate, 2% Saccharomyces ferment filtrate, 2% saccharide isomerate and 4% niacinamide. The study was conducted using a dualapplication technique of serum and cream with a brightening effect on facial hyperpigmentation among women in Indonesia. An open-label pre-post-test clinical trial was used. After six weeks of treatment, there was a significant decrease in the melanin index of the study participants. The use of cysteamine serum and cream appears to be a promising approach for treating hyperpigmentation disorders on the face.

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