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The relationship between fat mass, muscle mass, and BMi with severity degrees of knee joint osteoarthritis in postmenopausal women
Kasmar J.
Gazzetta Medica Italiana Archivio Per Le Scienze Mediche
Q4Abstract
BACKGROUND: Osteoarthritis is a disorder of the joints characterized by articular cartilage degeneration, subchondral bone changes, osteophyte formation, and synovial inflammation. There are numerous risk factors for knee osteoarthritis, including aging, knee injuries, obesity, changes in limb alignment, decreased muscle strength, women, menopausal status, strenuous physical labor, and genetic susceptibility. In women, body weight was significantly and positively associated with knee osteoarthritis, and fat mass and fat mass percentage among body weight components were significantly and closely associated with knee osteoarthritis. These findings suggest that the association between obesity and knee osteoarthritis is not solely based on mechanical stress but rather on fat mass, which contributes to inflammation. The aim of this study is to determine the relationship between fat mass, Body Mass Index (BMI), and muscle mass with the severity of osteoarthritis of the knee joint in postmenopausal women.METHODS: This cross-sectional study included 52 individuals with osteoarthritis. The body’s fat, BMI, and muscle mass were determined using bioelectrical impedance analysis. The diagnosis of knee osteoarthritis was based on the Kellgren-Lawrence criteria. Statistical analysis was done using the Chi-square Test. The test results are statistically significant if the P value is <0.05.RESULTS: A significant positive correlation was found between body fat mass (P=0.002) and BMI (P=0.043) with the severity of osteoarthritis in menopausal women. The odds ratio for fat mass was 8.125, and the BMI was 3.23. There is no correlation between body muscle mass and the severity of osteoarthritis in postmenopausal women (P=1.000).CONCLUSIONS: There is a significant correlation between postmenopausal women’s body fat mass and BMI and the severity of knee joint osteoarthritis. In comparison to other factors, body fat mass is the most influential.