The Impact of Moringa Oleifera and Folic Acid on Reducing Blood Glucose Levels in Alloxan-Induced Rattus Norvegicus

Abstract

Moringa leaf (Moringa oleifera) is a plant with antidiabetic activity.This study aims to determine the effectiveness of giving Moringa Oleifera and Folic Acid on blood glucose levels in female rats.Moringa Oleifera on blood glucose levels in rats after induced alloxan 120mg / kgBB.This study used alloxan as an inducer of diabetes mellitus in female rat test animals.15 female rats were divided into 5 treatment groups.Group I as a Negative Group (N), was given standard feed and Na-CMC, Positive Group (P) alloxan induction, group III treatment I (P1) alloxan induction and given EDK (MO), Group IV Treatment II (P2) alloxan induction and given Folic Acid (AF), Group V Treatment III (P3) alloxan induction and given MO and AF.The results showed that the combination of MO and AF could reduce blood glucose levels in female rats induced by alloxan.The results showed that the administration of Moringa Leaf Extract (MLE) and Folic Acid (AF) had a significant effect in reducing blood glucose levels of female rats p<0.05.The average decrease in rats' blood glucose levels in group P1 amounted to 151.00g/dl, P2 amounted to 374.33g/dl, and group P3 amounted to 82.67g/dl.The decrease in blood glucose levels is due to the presence of biochemical compounds that are thought to have a hyperglycemic effect.

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