# The effect of bitter melon (Momordica charantia l.) leaves extractonon glycated albumin in diabetic foot ulcers: Randomized controlled trial
> Rosyid F.N.

URL kanonis: https://discover.unhas.ac.id/publications/the-effect-of-bitter-melon-momordica-charantia-l-leaves-extractonon-glycated-alb
Jurnal / Konferensi: Bangladesh Journal of Medical Science
Tahun terbit: 2021
DOI: https://doi.org/10.3329/bjms.v20i2.51536
ISSN: 22234721
Kuartil SJR: Q3
Citations: 6

## Authors
- Rosyid F.N.

## Abstract
Objective: This study aims to prove the effect of supplementation of bitter melon leaves extract on glycemic status in diabetic foot ulcer (DFU).
 Materials and Methods: This study used a randomized, double-blinded, and placebo-controlled trial. Thirty DFU patients based on PEDIS 1-8 scores who met the criteria were divided into 2 groups consisting of 15 patients as a treatment group with the administration of bitter melon leaves extract at a dose of 6 g/day and 15 patients as a control group of with placebo. This intervention was conducted in 4 weeks. Glycemic status was measured by the value of glycated albumin and examined at baseline and at the end of treatment. Data were analyzed using paired t-test and independent t-test.
 Results: After 4 weeks of treatment, there was an increase in the baseline value of glycated albumin in the treatment group from 24.5 ± 11.7% to 25.8 ± 12.7% or an increase of 1.3 ± 6.3% and a decrease in the control group from 27.5 ± 13.1% to 25.8 ± 8.5% or a decrease of 1.7 ± 12.4%. The results of the analysis of the effect of supplementation of bitter melon leaves extract on the value of glycated albumin were not significant (p = 0.99).
 Conclusion: The supplementation of bitter melon leaf extract with a dose of 6 g / day did not significantly affect the value of glycated albumin.
 Bangladesh Journal of Medical Science Vol.20(2) 2021 p.281-287

## Keywords
- Medicine
- Glycemic
- Placebo
- Momordica
- Albumin
- Randomized controlled trial
- Diabetic foot
- Glycemic index
- Diabetes mellitus
- Internal medicine
- Gastroenterology
- Glycated haemoglobin
- Traditional medicine
- Type 2 diabetes
- Insulin
- Endocrinology
- Pathology
- Alternative medicine

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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