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Universitas Hasanuddin
Research output:Contribution to journalArticlepeer-review

The Art of Nanoimmunobiotechnomedicine in Depression Management

Anurogo D.

Advanced Pharmaceutical Bulletin

Q1
Published: 2025

Abstract

Purpose: To explore the role of nanoimmunobiotechnomedicine in depression management, emphasizing how nanotechnology and immunobiology offer innovative approaches to understanding and treating depression. We investigated the molecular mechanisms underlying depression and integrated multi-omics approaches such as genomics, epigenomics, and bioinformatics to advance therapeutic strategies. Methods: An interdisciplinary approach was applied, synthesizing data from epigenetics, nutrigenomics, and advanced bioinformatics. Furthermore, molecular and cellular neuroscience techniques were utilized alongside pharmacogenomics to deepen the understanding of depression. Results: Findings highlight the effectiveness of nano-based interventions, like targeted drug delivery systems and anti-inflammatory treatments, in reducing neuroinflammation and enhancing neuroplasticity. Multi-omics data show the importance of neurotrophic factors and gut-brain axis interactions in depression management. Additionally, pharmacogenetics suggests personalized treatment strategies, tailoring therapeutic responses based on individual genetic profiles. Conclusion: Nanoimmunobiotechnomedicine represents a frontier for personalized depression therapies. The integration of nanotechnology and immunobiology enhances bioavailability and specificity in targeting depressive disorders at the molecular level. This convergence of molecular biology, and bioinformatics studies holds significant potential to revolutionize depression treatment, offering more effective and individualized solutions for better mental health outcomes.

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10.34172/apb.025.42757

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PharmacogenomicsSciences
Personalized medicineSciences
Precision medicineSciences
Transformative learningSciences
Depression (economics)Sciences
MedicineSciences
Major depressive disorderSciences
PharmacogeneticsSciences
PsychiatrySciences
BiomedicineSciences
BioinformaticsSciences
PsychologySciences
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MEDLINESciences
Management of depressionSciences
Mental healthSciences
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