# Systemic lidocaine inhibits high-mobility group box 1 messenger ribonucleic acid expression and protein in BALB/c mice after closed fracture musculoskeletal injury
> Sirait R.

URL kanonis: https://discover.unhas.ac.id/publications/systemic-lidocaine-inhibits-high-mobility-group-box-1-messenger-ribonucleic-acid
Jurnal / Konferensi: Saudi Journal of Anaesthesia
Tahun terbit: 2018
DOI: https://doi.org/10.4103/sja.SJA_685_17
ISSN: 1658354X
Kuartil SJR: Q2
Citations: 17

## Authors
- Sirait R.

## Abstract
Intravenous administration of lidocaine effectively inhibited the inflammatory process in BALB/c mice that underwent closed fracture musculoskeletal injury by suppressing HMGB1 mRNA transcription and HMGB1 protein translation.

## Keywords
- HMGB1
- Medicine
- Lidocaine
- Messenger RNA
- Inflammation
- Pharmacology
- Sepsis
- Anesthesia
- Internal medicine
- Endocrinology
- Biology
- Gene
- Biochemistry

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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