# Synthesis and Antibacterial Evaluation of Cu(II), Co(II), and Mn(II) Complexes with Schiff Bases Derived from 5-Aminosalicylic Acid and o-Vanillin
> Shaheen M.A.

URL kanonis: https://discover.unhas.ac.id/publications/synthesis-and-antibacterial-evaluation-of-cuii-coii-and-mnii-complexes-with-schi
Jurnal / Konferensi: Russian Journal of General Chemistry
Tahun terbit: 2019
DOI: https://doi.org/10.1134/S1070363219080231
ISSN: 10703632
Kuartil SJR: Q4
Citations: 14

## Authors
- Shaheen M.A.

## Abstract
The current study is devoted to the synthesis of Schiff base ligand, HL, by condensation of 5-aminosalicylic acid with o-vanillin, followed by preparing its Cu(II), Co(II), Mn(II), and Zn(II) complexes, and their characterization. The Schiff base behaves as a bidentate ligand which forms tetrahedral complexes with Cu(II) and Zn(II), unlike Co(II) and Mn(II) that give octahedral complexes. The Schiff base ligand and its complexes with Cu2+, Co2+, Mn2+, and Zn2+ exhibit considerable antibacterial activity against some drug resistant reference strains and local isolates of S. aureus, E. Coli, P. aersginosa. Overall, the metal complexes exhibit more potent antibacterial activity than the ligand HL alone.

## Keywords
- Chemistry
- Schiff base
- Ligand (biochemistry)
- Denticity
- Antibacterial activity
- Octahedron
- Metal
- Aminosalicylic acid
- Medicinal chemistry
- Copper
- Polymer chemistry
- Stereochemistry
- Organic chemistry
- Crystal structure
- Bacteria
- Receptor
- Biochemistry
- Medicine
- Genetics
- Pharmacology
- Biology

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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