# Steroid therapy for Graves ophthalmopathy
> Condeng Y.H.

URL kanonis: https://discover.unhas.ac.id/publications/steroid-therapy-for-graves-ophthalmopathy
Jurnal / Konferensi: Current Issues in Pharmacy and Medical Sciences
Tahun terbit: 2025
DOI: https://doi.org/10.12923/cipms-2025-0025
ISSN: 2084980X
Kuartil SJR: Q3
Citations: 0

## Authors
- Condeng Y.H.

## Abstract
Graves' disease (GD) is a prevalent autoimmune disorder primarily affecting the thyroid gland, but it also impacts other organs, notably the eyes. Graves' ophthalmopathy (GO), an autoimmune condition associated with GD, affects the tissues behind the eyes, leading to inflammation and tissue remodeling. Risk factors for GO include radioactive iodine therapy, untreated hyperthyroidism, smoking and high serum TSH-receptor antibody levels. Management strategies involve various approaches, including pharmacological treatments such as glucocorticoids. High-dose systemic glucocorticoids are particularly effective in treating moderate to severe and active GO. This review was undertaken to consolidate current evidence on steroid therapy for GO, exploring the nuances of different administration routes, dosages and the potential need for second-line treatments. By providing a comprehensive analysis of the existing literature, this review aims to enhance clinicians' understanding of steroid therapy in GO, highlight gaps in current knowledge, and propose areas for future research.

## Keywords
- Medicine
- Graves' ophthalmopathy
- Disease
- Thyroid
- Inflammation
- Pharmacy
- Autoimmune disease
- Radioiodine therapy
- Intensive care medicine
- Internal medicine
- Immunology
- Steroid use
- Steroid
- Graves' disease
- Clinical pharmacology
- Clinical Practice
- Disease management
- Pharmacotherapy
- Antithyroid drugs
- Safety profile
- Dose
- MEDLINE
- Dermatology
- Biological drugs
- Thyroid disease

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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