# Serum interleukin-17 (IL-17) level in breast carcinoma before and after chemotherapy
> Ariyana

URL kanonis: https://discover.unhas.ac.id/publications/serum-interleukin-17-il-17-level-in-breast-carcinoma-before-and-after-chemothera
Jurnal / Konferensi: Medicina Clinica Practica
Tahun terbit: 2020
DOI: https://doi.org/10.1016/j.mcpsp.2020.100093
ISSN: 26039249
Kuartil SJR: Q4
Citations: 1

## Authors
- Ariyana

## Abstract
Breast cancer is a cellular disease which occurs from breast tissue with manifestation that failing to control the cellular proliferation and mutation. The purpose of this study is to identify the IL-17 level in breast carcinoma before and after chemotherapy. This research was a cross-sectional study with comparative analysis. Sampling was conducted using accidental sampling method. Interleukin-17 was analyzed using the Elisa method. Data were analyzed using paired T-test with an error tolerance of 0.05. The results showed significant differences before and after chemotherapy in breast cancer, with an increase in IL-17 levels of 46.36 pg/mL. Nonetheless, all the characteristics of good age, stage of cancer, and menopausal status, all experienced an increase in IL-17 levels after chemotherapy Patients with stage 2 cancer stages had the highest increase in IL-17 levels compared to the others, which was 62.09 pg/mL. IL-17 is a potential predictive biomarker for breast cancer therapy.

## Keywords
- Breast cancer
- Medicine
- Chemotherapy
- Breast carcinoma
- Oncology
- Internal medicine
- Stage (stratigraphy)
- Cancer
- Interleukin 6
- Biomarker
- Cytokine
- Biology
- Paleontology
- Biochemistry

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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