# SARS-CoV-2 reinfection and implications for vaccine development
> Nainu F.

URL kanonis: https://discover.unhas.ac.id/publications/sars-cov-2-reinfection-and-implications-for-vaccine-development
Jurnal / Konferensi: Human Vaccines and Immunotherapeutics
Tahun terbit: 2020
DOI: https://doi.org/10.1080/21645515.2020.1830683
ISSN: 21645515
Kuartil SJR: Q2
Citations: 65

## Authors
- Nainu F.

## Abstract
Coronavirus disease 2019 (COVID-19) pandemic continues to constitute a public health emergency of international concern. Multiple vaccine candidates for COVID-19, which is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), have entered clinical trials. However, some evidence suggests that patients who have recovered from COVID-19 can be reinfected. For example, in China, two discharged COVID-19 patients who had recovered and fulfilled the discharge criteria for COVID-19 were retested positive to a reverse transcription polymerase chain reaction (RT-PCR) assay for the virus. This finding is critical and could hamper COVID-19 vaccine development. This review offers literature-based evidence of reinfection with SARS-CoV-2, provides explanation for the possibility of SARS-CoV-2 reinfection both from the agent and host points of view, and discusses its implication for COVID-19 vaccine development.

## Keywords
- Coronavirus disease 2019 (COVID-19)
- Pandemic
- Virology
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- Medicine
- Coronavirus
- Immunology
- 2019-20 coronavirus outbreak
- Disease
- Infectious disease (medical specialty)
- Outbreak
- Internal medicine

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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