# SARS-CoV-2 infection during pregnancy and pregnancy-related conditions: Concerns, challenges, management and mitigation strategies–a narrative review
> Kumar R.

URL kanonis: https://discover.unhas.ac.id/publications/sars-cov-2-infection-during-pregnancy-and-pregnancy-related-conditions-concerns
Jurnal / Konferensi: Journal of Infection and Public Health
Tahun terbit: 2021
DOI: https://doi.org/10.1016/j.jiph.2021.04.005
ISSN: 18760341
Kuartil SJR: Q1
Citations: 57

## Authors
- Kumar R.

## Abstract
The ongoing coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), is a global public health problem. The SARS-CoV-2 triggers hyper-activation of inflammatory and immune responses resulting in cytokine storm and increased inflammatory responses on several organs like lungs, kidneys, intestine, and placenta. Although SARS-CoV-2 affects individuals of all age groups and physiological statuses, immune-compromised individuals such as pregnant women are considered as a highly vulnerable group. This review aims to raise the concerns of high risk of infection, morbidity and mortality of COVID-19 in pregnant women and provides critical reviews of pathophysiology and pathobiology of how SARS-CoV-2 infection potentially increases the severity and fatality during pregnancy. This article also provides a discussion of current evidence on vertical transmission of SARS-CoV-2 during pregnancy and breastfeeding. Lastly, guidelines on management, treatment, preventive, and mitigation strategies of SARS-CoV-2 infection during pregnancy and pregnancy-related conditions such as delivery and breastfeeding are discussed.

## Keywords
- Pregnancy
- Medicine
- Cytokine storm
- Breastfeeding
- Immune system
- Pandemic
- Immunology
- Intensive care medicine
- Disease
- Public health
- Coronavirus disease 2019 (COVID-19)
- Infectious disease (medical specialty)
- Pediatrics
- Internal medicine
- Pathology
- Biology
- Genetics

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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