Role of genetic polymorphisms of angiotensin converting enzyme to cardiovascular endurance in men ages 13-14 years after fartlek training for 3 months

Abstract

Physical ability is influenced by two factors, namely environmental and genetic factors. Environmental factors that influence are exercise intensity, nutritional intake, and age. Another factor that is not less important in influencing cardiovascular endurance is genetic factors. One of gene variation that is considered to determine the athlete's potential is the variation in the ACE gene symbolized by I and D. The ACE gene insertion/deletion polymorphism (I/D) has an important relationship with cardiovascular fitness with genotype II which shows a lower level of cardiorespiratory fitness with VO2max than the Non II genotype (ID and DD). The purpose of this study was to assess how the role of the ACE gene in male cardiovascular endurance aged 13–14 years. This study provides a three-month fartlek training program and conducts cardiovascular endurance tests before and after taking a three-month fartlek training program. In group II genotype subjects showed the results of increased cardiovascular endurance compared to the Non II genotype subject group. Research can conclude a strong relationship between the variation of the angiotens in converting enzyme gene II genotype against male cardiovascular age 13–14 years.

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