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Relationship between Pneumonia Severity Index and CURB-65 with mortality in COVID-19 patient
Darmawan I.
Gazzetta Medica Italiana Archivio Per Le Scienze Mediche
Q4Abstract
BACKGROUND: Coronavirus disease 2019 (COVID-19) is an infectious virus. Despite many advances treatment since beginning of pandemic, the impact due to mortality burden continues to drive evaluation of screening tools as mortality prediction tools. As prediction instruments for pneumonia severity and mortality in the community, the Pneumonia Severity Index (PSI) and CURB-65 have received approval. The aim of this study was to ascertain the correlation between the two severity scores with mortality of COVID-19 patient.METHODS: This study has a retrospective cross-sectional design. It includes 3028 sample using medical record data from COVID-19 patients who were admitted to Dr. Wahidin Sudirohusodo Hospital between January 2020 to December 2022. Statistical test results were considered significant if the test P value was <0.05.RESULTS: From a total 3028 patient data, 1565 met inclusion criteria, also including 467 patients who died. There was a significant association of PSI and CURB-65 severity scores with mortality of COVID-19 patients (P<0.001). Multivariate analysis revealed that PSI Score appeared more accurate than CURB-65 as a predictor of mortality >48 hours (Wald=65.67 P<0.001) vs. (Wald=32.07 P<0.001) and <48 hours (Wald=45.36 P<0.001) vs. (Wald=28.13 P<0.001).CONCLUSIONS: There is a relationship between PSI and CURB-65 severity scores with mortality of COVID-19 patients. Compared with CURB-65, PSI Score seems more accurate in predicting on less and more than 48 hours mortality of COVID-19 patients.