# Analysis of the Relationship Between Soluble Cd40 Ligand and Homeostasis Model Assessment of Insulin Resistance in Obese Non-Diabetic Subjects > Ismi N. URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85214361493 Jurnal / Konferensi: Gaceta Medica De Caracas Tahun terbit: 2024 DOI: https://doi.org/10.47307/GMC.2024.132.4.12 ISSN: 03674762 Kuartil SJR: Q4 Citations: 0 ## Authors - Ismi N. ## Abstract Obesity is a complex multifactorial disease characterized by the accumulation of body fat, leading to adverse effects on one’s well-being. Obesity has a strong association with insulin resistance. Insulin resistance can lead to a range of health issues, including type II diabetes mellitus, cardiovascular disease, and other metabolic syndrome diseases. A method that can be employed to evaluate insulin resistance is the measurement of HOMA-IR. sCD40L is the soluble form of the CD40L molecule released on the cell surface through proteolysis. There is evidence that the sCD40L level is a strong predictor of cardiovascular risk, and enhanced levels of CD40L were reported in patients with hypercholesterolemia, diabetes mellitus, and acute coronary syndromes. ## Keywords - Insulin resistance - Homeostasis - Internal medicine - Diabetes mellitus - Endocrinology - Glucose homeostasis - Medicine --- Sumber: Discover Unhas — RIMS Universitas Hasanuddin. Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.