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Comparison of insulin resistance incidence in young adults with metabolic syndrome based on the NCEP-ATP III and the IDF criteria
Sambo G.P.
Gazzetta Medica Italiana Archivio Per Le Scienze Mediche
Q4Abstract
BACKGROUND: Insulin resistance usually occurs when a person gains weight and accumulates fat. Metabolic syndrome refers to a group of closely connected medical conditions. The aim of this study was to compare NCEP-ATP III criteria and IDF criteria to predict insulin resistance incidence in young adults with metabolic syndrome.METHODS: A cross-sectional study with 99 subjects aged between 25-40 years who were not pregnant and did not have diabetes mellitus. Those with diabetes were excluded from the study. The study utilized the HOMA-IR cut-off at 2.03 in the third tertile. Statistical analysis was conducted using the Kolmogorov-Smirnov Test and χ2 test.RESULTS: Subjects with central obesity 77 (77.8%); elevated fasting blood glucose 6 (6.1%); elevated triglyceride 81 (81.8%); decreased HDL 20 (20.2%); and insulin resistance with HOMA-IR cut-off 2.03 is 33 (33.3%). NCEP-ATP III and IDF revealed that 10 (30.3% and 21 (63.6%) had insulin resistance respectively. NCEP-ATP III found that young adults with insulin resistance had a 28.3 times greater risk than IDF, which only found 7.9 times for developing metabolic syndrome.CONCLUSIONS: NCEP-ATP III criteria were more effective in predicting insulin resistance compared to IDF criteria in young adults with metabolic syndrome.