# Comparative Analysis of C-Reactive Protein and Procalcitonin Levels in the Severity of COVID-19 Patients
> Alawiyah T.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85189798469
Jurnal / Konferensi: Indonesian Journal of Clinical Pathology and Medical Laboratory
Tahun terbit: 2024
DOI: https://doi.org/10.24293/ijcpml.v30i2.2156
ISSN: 24774685
Kuartil SJR: Q4
Citations: 0

## Authors
- Alawiyah T.

## Abstract
Coronavirus Disease 2019 (COVID-19) is a systemic disease characterized by mild to critical symptoms with a high risk of mortality. Fast and precise inflammatory markers are needed to predict the severity and prognosis of COVID-19 to decrease the mortality rate. The elevated levels of C-Reactive Protein (CRP) and procalcitonin may predict an increased risk of aggravation in COVID-19 patients. This study aimed to analyze the CRP and procalcitonin levels of COVID-19 severity. This was a cross-sectional retrospective study involving 160 COVID-19 patients at Dr. Wahidin Sudirohusodo Hospital. Subjects were grouped based on the severity of COVID-19 (mild, moderate, severe, critical). The difference in CRP and procalcitonin levels based on the severity of COVID-19 was analyzed using the Kruskal-Wallis test and the Spearman correlation test. The age of participants in this study ranged from 19-87 years old. The higher CRP and procalcitonin level shows heavier the severity of COVID-19 (p<0.001). This indicated a significant difference between CRP, procalcitonin levels, and the severity of COVID-19. This study showed that there was a significant correlation between CRP and procalcitonin with the severity of COVID-19, CRP (p<0.001) and procalcitonin (p<0.001).

## Keywords
- Procalcitonin
- Medicine
- Coronavirus disease 2019 (COVID-19)
- 2019-20 coronavirus outbreak
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- Internal medicine
- C-reactive protein
- Intensive care medicine
- Virology
- Inflammation
- Disease
- Sepsis
- Outbreak
- Infectious disease (medical specialty)

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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