# Hypotestosterone in Male with Obesity
> Kurniawan L.B.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85188622316
Jurnal / Konferensi: Indonesian Journal of Clinical Pathology and Medical Laboratory
Tahun terbit: 2021
DOI: https://doi.org/10.24293/ijcpml.v27i2.1525
ISSN: 24774685
Kuartil SJR: Q4
Citations: 1

## Authors
- Kurniawan L.B.

## Abstract
Obesity can be defined as the excess of body fat. The prevalence of obesity worldwide increases in the last decades andcauses a higher risk of cardiovascular diseases. Male subjects tend to develop visceral (abdominal) obesity, which producespro-inflammatory adipokines. Obesity in males is associated with low testosterone levels. Several mechanisms have beenproposed to explain the link between male obesity and hypotestosterone, including increased aromatization oftestosterone to form estradiol, suppressing the Hypothalamus-Pituitary (HPT) axis due to pro-inflammatory adipokines, anddecrease of Sex Hormone Binding Globulin (SHBG) production. Because hypotestosterone in males with obesity is afunctional but reversible condition, it is essential to screen testosterone levels in obese males for early intervention andtreatment.

## Keywords
- Medicine
- Obesity
- Adipokine
- Sex hormone-binding globulin
- Internal medicine
- Endocrinology
- Testosterone (patch)
- Abdominal obesity
- Leptin
- Adiponectin
- Hormone
- Androgen
- Metabolic syndrome
- Insulin resistance

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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