# The Influence of Number of Ligated Veins in Varicocele Patients Undergoing Microsurgical Varicocelectomy in Postoperative Pain and Sperm Parameters Outcome > Syarief A.N. URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85170355328 Jurnal / Konferensi: Medical Archives Tahun terbit: 2023 DOI: https://doi.org/10.5455/medarh.2023.77.299-305 ISSN: 0350199X Kuartil SJR: Q3 Citations: 2 ## Authors - Syarief A.N. ## Abstract Background: The influence of the number of veins that should be ligated in varicocele surgery on postoperative pain and testicular function is not clearly understood. Objective: The aim of this study was to investigate the number of Internal Spermatic Vein (ISV) ligated in postoperative pain and sperm parameters outcome. Methods: Relevant studies were collected and systematically reviewed from Medline, Scopus, and Cochrane databases. This study followed the PRISMA guideline. The mean difference (MD), odds ratio (OR), and 95% confidence intervals (CIs) were measured in the assessment of the outcome. Revman 5.4 was used in data analysis. Results: The pooled meta-analysis demonstrated that complete pain resolution was significantly higher in patients undergoing varicocelectomy procedures with more than ten vein numbers ligated with OR 1.92, 95% CI (1.03, 3.60). Improvement of sperm parameters of change in sperm concentration was also significantly observed in patients with more than ten vein numbers ligated MD 32.79, 95% CI (23.13, 42.45). However, the number of veins ligated was not associated with the change in sperm motility MD 9.69 with 95% CI (-12.32, 31.71). Conclusion: The number of veins ligated intraoperatively determined pain relief and sperm concentration improvement. This study showed that varicocelectomy results improved with greater ISV ligation. ## Keywords - Varicocele - Medicine - Meta-analysis - Sperm - Odds ratio - Confidence interval - Ligation - Cochrane Library - Spermatic Vein - Sperm motility - Vein - Semen analysis - Surgery - Urology - Internal medicine - Andrology - Infertility - Biology - Pregnancy - Genetics --- Sumber: Discover Unhas — RIMS Universitas Hasanuddin. Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.