# Changes in osteoblast and osteoclast cell count after moringa oleifera leaf extract administration during orthodontic tooth movement > Syarif R.D. URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85138145570 Jurnal / Konferensi: Journal of Dentomaxillofacial Science Tahun terbit: 2020 DOI: https://doi.org/10.15562/jdmfs.v5i2.1081 ISSN: 25030817 Kuartil SJR: Q3 Citations: 8 ## Authors - Syarif R.D. ## Abstract Objective: The aim of this study was to analyze the effect of moringa leaf extract administration at 5%, 10%, and 20% concentration toward osteoblast and osteoclast cell count in tension area of Cavia cobaya tooth movement. Matrial and Methods: This study was an experimental research with post test only control group design conducted on Cavia Cobaya. The samples were divided into 4 groups, namely control group (given orthodontic forces), P1 group (given orthodontic forces and Moringa oleifera extract at 5% concentration), P2 group (given orthodontic forces and Moringa oleifera extract at 10% concentration) and P3 group (given orthodontic forces and Moringa oleifera extract at 20% concentration). The samples were sacrificed in day 15 and the tissue were collected for histological examination to examine osteoblast and osteoclast cell count.Results: The Anova test showed a significant difference of osteoblast and osteoclast cell count among groups (p<0.05).Conclusion: Moringa leaves extract administration at 20% concentration for 7 days shows higher number of osteoblast and osteoclast compared to control group, 5% and 10% extract group. ## Keywords - Moringa - Osteoclast - Osteoblast - Traditional medicine - Medicine - Dentistry - Chemistry - Internal medicine - Biochemistry - In vitro - Receptor --- Sumber: Discover Unhas — RIMS Universitas Hasanuddin. Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.