# Congenital talipes equinovarus: A literature review > Mustari M.N. URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85136139810 Jurnal / Konferensi: Annals of Medicine and Surgery Tahun terbit: 2022 DOI: https://doi.org/10.1016/j.amsu.2022.104394 ISSN: 20490801 Citations: 23 ## Authors - Mustari M.N. ## Abstract Congenital talipes equinovarus (CTEV) is a congenital disability characterized by leg deformities in the cavus, adducts, varus, and equinus. The etiology of CTEV is poorly understood, despite its incidence ranging from 0.76 to 3.49 cases per 1000 live births in Indonesia. CTEV involves the fixation of the foot in the adducts, varus, and equinus with concurrent soft tissue anomalies. Despite advances in treatment, disability often persists. Theoretical models have been proposed for neurological, vascular, connective tissue, bone, and muscular causes; however, the currently available data suggests that mild cases are associated with intrauterine position. CTEV's etiology appears to involve a hereditary component, as its prevalence varies by ethnic group. Genetic factors have been identified in 24–50% of cases, depending on the community studied. Based on a complex segregation analysis, the most plausible inheritance pattern is a single large-effect gene interacting with a polygenic background. HIGHLIGHTS CTEV is a congenital disability characterized by leg deformities in the cavus, adducts, varus, and equinus. In Indonesia, its incidence ranges from 0.76 to 3.49 cases per 1000 live births. Genetic factors have been identified in 24–50% of cases, depending on the community studied. ## Keywords - Medicine - Congenital talipes equinovarus - Clubfoot - Surgery - Dermatology - Deformity --- Sumber: Discover Unhas — RIMS Universitas Hasanuddin. Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.