# Malnutrition in children associated with low insulin-like growth factor binding protein-3 (IGFBP-3) levels
> Rahmawati D.A.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85121235860
Jurnal / Konferensi: Gaceta Sanitaria
Tahun terbit: 2021
DOI: https://doi.org/10.1016/j.gaceta.2021.07.019
ISSN: 02139111
Kuartil SJR: Q3
Citations: 2

## Authors
- Rahmawati D.A.

## Abstract
OBJECTIVE: This study aimed to compare serum levels of Insulin-like Growth Factor Binding Protein-3 in children with malnutrition and good nutritional status. METHOD: This cross-sectional study included 41 participants consisting of 31 malnourished, 10 well-nourished children aged between 36 and 60 months. Demographic data of participants were obtained utilizing a questionnaire. Nutritional status was determined by calculating the Z-score of body weight for age, height for age, and body weight for height indices using the WHO classification. IGFBP-3 levels were determined by the Enzyme-Linked Immunosorbent Assay (ELISA) method. RESULT: Median serum IGFBP-3 levels in malnourished children were found to be lower i.e. 0.35mcg/mL (minimum-maximum: 0.04-1.52mcg/mL) compared to well-nourished children 1.52ng/mL (minimum-maximum 0.47-3.17mcg/mL). CONCLUSION: Serum IGFBP-3 levels can be used as indicators to assess nutritional status.

## Keywords
- Malnutrition
- Medicine
- Insulin-like growth factor-binding protein
- Body weight
- Insulin
- Cross-sectional study
- Internal medicine
- Pediatrics
- Insulin-like growth factor
- Endocrinology
- Physiology
- Growth factor
- Pathology
- Receptor

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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