# Autonomic dysregulation in acute ischemic stroke patient with insomnia
> Suminar D.A.A.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85107084958
Jurnal / Konferensi: Medicina Clinica Practica
Tahun terbit: 2021
DOI: https://doi.org/10.1016/j.mcpsp.2021.100206
ISSN: 26039249
Kuartil SJR: Q4
Citations: 3

## Authors
- Suminar D.A.A.

## Abstract
This study aimed to assess autonomic dysregulation by measuring Heart Rate Variability (HRV) parameters in acute ischemic stroke patients with insomnia. This was a descriptive observational study on 5 participants (4 females and one male) with acute ischemic stroke and insomnia. All participants were assessed through the Pittsburgh Sleep Quality Index (PSQI) and Insomnia Severity Index (ISI) and then tested using a Polar H10 device for 5 min recording during night sleep. The collected data analyzed by Kubios HRV Analysis Software 3.2 (MATLAB, Kuopio, Finland). This study showed that all participants (age 51.2 ± 12.61) had subthreshold to moderate insomnia based on ISI (14.8 ± 2.48) and had poor sleep quality based on PSQI (16.4 ± 3.72). There was an increase of mean heart rate (HR) (81.8 ± 13.86), root mean square of successive differences (rMSSD) (46.6 ± 38.05), and sympathetic nervous system index (SNS Index) (1.542 ± 1.567), as well as the decrease of standard deviation of normal-normal interval (SDNN) (37.8 ± 20.53), low frequency (LF) (449.2 ± 371.8), high frequency (HF) (812.6 ± 773.8), LF/HF (1.89 ± 1.72), and parasympathetic nervous system index (PNS Index) (−0.462 ± 1.210). The Analysis of HRV showed an autonomic dysregulation in the form of parasympathetic dysfunction and sympathetic hyperactivation during night sleep in the acute phase of ischemic stroke with insomnia.

## Keywords
- Pittsburgh Sleep Quality Index
- Heart rate variability
- Insomnia
- Medicine
- Autonomic nervous system
- Cardiology
- Internal medicine
- Heart rate
- Anesthesia
- Physical therapy
- Blood pressure
- Sleep quality
- Psychiatry

---
Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.