# Immune response during the onset of coliform mastitis in dairy cows vaccinated with STARTVAC®
> Kawai K.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85099420110
Jurnal / Konferensi: Animal Science Journal
Tahun terbit: 2021
DOI: https://doi.org/10.1111/asj.13502
ISSN: 13443941
Kuartil SJR: Q2
Citations: 5

## Authors
- Kawai K.

## Abstract
The immune response during the onset of coliform mastitis in vaccinated cows was investigated by measuring lactoferrin (LF), interleukin-8 (IL-8), and interleukin-1β (IL-1β) concentrations and somatic cell counts in 28 milk samples at the onset of acute coliform mastitis (ACM) and 73 milk samples at the onset of peracute coliform mastitis (PCM). Vaccinated ACM, unvaccinated ACM, and vaccinated PCM showed significantly higher values for LF and IL-1β levels than unvaccinated PCM (p < .01). The IL-8 concentration was lower in vaccinated PCM than in unvaccinated PCM (p < .05). There was no significant difference in somatic cell counts for each parameter. There were no significant differences in the parameters between vaccinated and unvaccinated ACM cows, or vaccinated ACM and PCM cows. From the above results, it is suggested that mastitis vaccination improved the early immune response, particularly at the onset of PCM, and played a large role in host defense against the initial infection.

## Keywords
- Mastitis
- Immune system
- Lactoferrin
- Somatic cell count
- Vaccination
- Animal science
- Immunology
- Biology
- Medicine
- Microbiology
- Pregnancy
- Ice calving
- Genetics
- Lactation

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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