# Histometry analysis of osteoclasts, osteoblasts and fibroblasts in immediate placement implants with addition of aloe vera extract > Machmud E. URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85066758817 Jurnal / Konferensi: Pesquisa Brasileira Em Odontopediatria E Clinica Integrada Tahun terbit: 2019 DOI: https://doi.org/10.4034/PBOCI.2019.191.74 ISSN: 15190501 Kuartil SJR: Q2 Citations: 5 ## Authors - Machmud E. ## Abstract Objective: To analyze the effect of immediate placement of implants with extract from the new bone formation histometically.  Material and Methods: In this true-experimental design with randomized post test control group, 9 mongrel dogs weighing 10 to 12 kg were used, which were divided into 3 groups, based on observation time of 14 days, 28 days and 56 days. On the installation of implants ( ∅ 3.5x10 mm) sequentially, the former socket extraction of the lower jaw’s right second premolar tooth in the study sample injected 10% Aloe vera gel extract and left second left premolar tooth without injection of 10% Aloe vera extract. To compare independent groups use the Mann-Whitney test. All analysis were carried out using SPSS version 20.  Results: There was an increase in the number of osteoblast cells in both treatment and control groups, but the value of the treatment group was greater.  There were significant differences in the number of osteoblast cells between the treatment and control groups 14 days (p=0.019), 28 days: (p=0.018), and 56 days (p=0.009).  There were no  significant differences in the number of fibroblast cells between the treatment and control groups (p>0.05). But at observations 28 and 56 days, it was showed a significant difference in the number of fibroblast cells between the treatment and control groups (p=0.353 and p=0.024, respectively). Conclusion: Immediate placement of implants with 10% Aloe vera extract gel on extracted socket increases the number of osteoblasts and suppresses the number of osteoclasts and fibroblasts. ## Keywords - Aloe vera - Dentistry - Medicine - Chemistry - Traditional medicine --- Sumber: Discover Unhas — RIMS Universitas Hasanuddin. Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.