# GC-MS analysis and antimicrobial activity determination of Citrus medica L. var proper leaf essential oil from South Sulawesi against skin pathogen microorganism > Aliyah URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85038383215 Jurnal / Konferensi: Iop Conference Series Materials Science and Engineering Tahun terbit: 2017 DOI: https://doi.org/10.1088/1757-899X/259/1/012001 ISSN: 17578981 Citations: 9 ## Authors - Aliyah ## Abstract A research about Citrus medica L. var sarcodactylis had been conducted and it showed a significant antimicrobial activity, thus drive our curiosity to investigate the other variety from the same species, Citrus medica L. var proper. This research focuses in chemical compound study and antimicrobial activity screening against Staphylococcus aureus, Propionibacterium acne, and Candida albicans of Citrus medica L. var Proper leaves' essential oil. The essential oil is distillated from fresh leaves by hydrodestillation. The chemical compound was analysed using GC-MS instrument while the antimicrobial activity was tested using disk diffusion method. The results showed that the major component of the essential oil was Z-citral, citral and limonene compounds. The antimicrobial activity test results against the test microorganism are 9.15±0.15 mm, 11.15±1.3 mm and 8.02±0.48 mm, consecutively, for Staphylococcus aureus, Propionibacterium acne and Candida albicans. ## Keywords - Antimicrobial - Essential oil - Microorganism - Traditional medicine - Biology - Botany - Microbiology - Medicine - Bacteria - Genetics --- Sumber: Discover Unhas — RIMS Universitas Hasanuddin. Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.