# Within-host selection of drug resistance in a mouse model of repeated interrupted treatment of Plasmodium yoelii infection
> Nuralitha S.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_85019920877
Jurnal / Konferensi: Malaria Journal
Tahun terbit: 2017
DOI: https://doi.org/10.1186/s12936-017-1860-6
ISSN: 14752875
Kuartil SJR: Q1
Citations: 3

## Authors
- Nuralitha S.

## Abstract
RIT of P. yoelii infected mice led to rapid development of resistance to atovaquone and pyrimethamine. The dose dependent selection of resistance mutants to atovaquone observed during RIT might reflect the outcome of two different causes of malaria treatment failure in human, repeated incomplete treatment with therapeutic dose and repeated inadequate treatment associated with sub-therapeutic dose, and need to be systematically investigated.

## Keywords
- Atovaquone
- Plasmodium yoelii
- Malaria
- Biology
- Drug resistance
- Plasmodium falciparum
- Pyrimethamine
- Virology
- Pharmacology
- Immunology
- Parasitemia
- Microbiology

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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