Antitumor activity of Eubacterium lentum (TYH-11) on various tumor cell lines

Abstract

The proliferation of Meth-A and AH6oCfibrosarcoma inoculated intraperitoneally was suppressed in all ntice given Eubacteriun lentu,tt (TYH-11) intraperitoneally. The proliferation of MH 134 hepatona and Ll2Io lytnphoitl ieukenria was also suppressed in sonte of the nice receivingthis strain. Artrongforns of solidtutnors, this bacterial strain curedsone micewith MHl34 hepanira The sunival tines of nice inoculated with 016 melanona were prolonged by injection of Eubacteriurn lentutn. The antitutttor activity induced by pre-adninistration of this sttain against MHli4 hepator,ra, L12l ) Iyntphoid leukena and p388 leukctnia cells was superior to that produced by post-administration. This strain, however, had no antitunror activity against EL4 lyntphonrc and lzwis lung carcinotna.

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