# A new polyoxygenated cyclohexane and other constituents from Kaempferia rotunda and their cytotoxic activity
> Lallo S.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_84905635469
Jurnal / Konferensi: Natural Product Research
Tahun terbit: 2014
DOI: https://doi.org/10.1080/14786419.2014.945175
ISSN: 14786419
Kuartil SJR: Q2
Citations: 13

## Authors
- Lallo S.

## Abstract
The isolation of secondary metabolites from a methanolic extract of Kaempferia rotunda yielded 12 compounds (1-12), including a new polyoxygenated cyclohexane compound, (-)-3-acetyl-4-benzoyl-1-benzoyloxymethyl-1,6-diepoxycyclohexan-2,3,4,5-tetrol (1). The structures of the isolated compounds were determined based on their spectroscopic data and comparison with references. All of the isolated compounds were tested for their cytotoxic activity against pancreatic (PSN-1) and breast (MDA-MB231) cancer cell lines. Compound 12 showed moderate cytotoxic activity against PSN-1 and MDA-MB231 without showing any cytotoxicity against the normal cell line, TIG-3.

## Keywords
- Cyclohexane
- Cytotoxic T cell
- Traditional medicine
- Chemistry
- Stereochemistry
- Botany
- Biology
- Organic chemistry
- Medicine
- In vitro
- Biochemistry

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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