# Antiplasmodial evaluation of one compound from Calophyllum flavoranulum
> Abbas J.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_84905015281
Jurnal / Konferensi: Indonesian Journal of Chemistry
Tahun terbit: 2014
DOI: https://doi.org/10.22146/ijc.21257
ISSN: 14119420
Kuartil SJR: Q3
Citations: 7

## Authors
- Abbas J.

## Abstract
Calophyllum flavoranulum (Clusiaceae family) is a big tree and medical plants from the tropical rain forest of the Indonesian continent. The organic extracts from stem bark yielded phenyl coumarin. The structure was elucidated with the aid of spectroscopic technique. Antiplasmodial activities of isolated compound was tested in vivo against Plasmodium berghei parasite and showed the best antiplasmodial activity. New flavoranulum coumarin compound showed activity against P. berghei parasite with inhibition growth 0, 31.33, 40, 30.67, 46 and 34% at dosage 1.1x10-10, 1.1x10-9, 1.1x10-8, 1.1x10-7, 1.1x10-6, and 1.1x10-5 mg/mL, respectively. Flavoranulum coumarin very active as antiplasmodial, and at 3 and 4 day incubation all of parasite were died.

## Keywords
- Clusiaceae
- Plasmodium berghei
- Chemistry
- Coumarin
- Traditional medicine
- Parasite hosting
- Bark (sound)
- Organic chemistry
- Biology
- World Wide Web
- Computer science
- Medicine
- Ecology

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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