# Syntheses of the proposed structures of poison-frog alkaloids 179 and 207E and their inhibitory effects on neuronal nicotinic acetylcholine receptors
> Toyooka N.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_38549131753
Jurnal / Konferensi: Synlett
Tahun terbit: 2008
DOI: https://doi.org/10.1055/s-2007-1000831
ISSN: 09365214
Kuartil SJR: Q3
Citations: 11

## Authors
- Toyooka N.

## Abstract
Syntheses of the structures postulated for 179 and 207E, members of a proposed new class of poison-frog alkaloids, 6,7-dehydro-5,8-disubstituted indolizidines, are described. The FT-IR spectrum and GC retention time of the synthetic 207E were different from those of the natural product; consequently the original structure of 207E needs to be revised. It is likely that the position of the double bond is instead at the 7,8-position.

## Keywords
- Chemistry
- Inhibitory postsynaptic potential
- Acetylcholine receptor
- Nicotinic agonist
- Natural product
- Acetylcholine
- Stereochemistry
- Nicotinic acetylcholine receptor
- Receptor
- Biochemistry
- Pharmacology
- Neuroscience
- Medicine
- Biology

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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