# Cyclic depsipeptides, ichthyopeptins A and B, from Microcystis ichthyoblabe
> Zainuddin E.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_34548015425
Jurnal / Konferensi: Journal of Natural Products
Tahun terbit: 2007
DOI: https://doi.org/10.1021/np060303s
ISSN: 01633864
Kuartil SJR: Q1
Citations: 65

## Authors
- Zainuddin E.

## Abstract
Bioassay-guided isolation of antiviral compounds from the cultured cyanobacterium Microcystis ichthyoblabe provided two novel cyclic depsipeptides, ichthyopeptins A (1) and B (2). Their structures were determined by 1D (1H and 13C) and 2D (COSY, TOCSY, ROESY, HMQC, and HMBC) NMR spectra, ESIMS-MS, and amino acid analysis. The fraction containing both cyclic depsipeptides exhibited antiviral activity against influenza A virus with an IC50 value of 12.5 microg/mL.

## Keywords
- Depsipeptide
- Stereochemistry
- Bioassay
- Chemistry
- Two-dimensional nuclear magnetic resonance spectroscopy
- Biological activity
- Cyclic peptide
- Biology
- In vitro
- Biochemistry
- Peptide
- Genetics

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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