# Constituents of Zingiber aromaticum and their CYP3A4 and CYP2D6 inhibitory activity
> Subehan

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_21144456408
Jurnal / Konferensi: Chemical and Pharmaceutical Bulletin
Tahun terbit: 2005
DOI: https://doi.org/10.1248/cpb.53.333
ISSN: 00092363
Kuartil SJR: Q3
Citations: 14

## Authors
- Subehan

## Abstract
A new sesquiterpene 2,9-humuladien-6-ol-8-one (1) was isolated from methanol extract of Zingiber aromaticum, along with 15 known compounds. The structures of the isolated compounds were elucidated on the basis of spectroscopic analyses. The isolated compounds were tested for their inhibitory activity on the metabolism mediated by cytochrome P450 3A4 (CYP3A4) and CYP2D6.

## Keywords
- Chemistry
- CYP3A4
- Sesquiterpene
- Cytochrome P450
- Stereochemistry
- Inhibitory postsynaptic potential
- Traditional medicine
- Pharmacognosy
- Methanol
- Biological activity
- Enzyme
- Biochemistry
- Organic chemistry
- In vitro
- Biology
- Medicine
- Neuroscience

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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