# Waist circumference, blood glucose, serum myeloperoxidase, xanthine oxidase and oxidized low‑density lipoprotein as determinants of blood pressure among adults with abdominal obesity
> Kurniawan L.B.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_105048908650
Jurnal / Konferensi: Biomedical Reports
Tahun terbit: 2026
DOI: https://doi.org/10.3892/br.2026.2191
ISSN: 20499434
Kuartil SJR: Q2
Citations: 0

## Authors
- Kurniawan L.B.

## Abstract
Obesity is a risk factor for increased blood pressure and diabetes, in which the relationship is mediated by the action of several pro-inflammatory mediators such as myeloperoxidase (MPO), xanthine oxidase (XO) and oxidized low-density lipoprotein (Ox-LDL).The present study aimed to evaluate the contribution of serum MPO, XO and Ox-LDL as determinants of blood pressure in adults with abdominal obesity.A total of 86 adults with abdominal obesity were recruited, then waist circumference (WC), fasting serum glucose (FSG), MPO, XO and serum Ox-LDL were measured.The contributions of these parameters to systolic blood pressure (SBP) and diastolic blood pressure (DBP) were then assessed.Multivariate analysis revealed that the determinant factors of SBP were WC, FSG, MPO and XO (β=0.418,0.328, 0.282 and 0.248 respectively; all P<0.05; adjusted R 2 =41.5%), while the determinants of DBP were FSG, WC and MPO (β=0.310,0.284 and 0.274, respectively; all P<0.05; adjusted R 2 =24.8%).In conclusion, MPO has a role as a determinant factor for SBP and DBP, whilst XO has a role as a determinant factor for SBP, and Ox-LDL does not have a significant role in blood pressure.

## Keywords
- Internal medicine
- Abdominal obesity
- Endocrinology
- Medicine
- Waist
- Blood pressure
- Xanthine oxidase
- Obesity
- Lipoprotein
- Lipoprotein(a)
- Waist–hip ratio
- Blood lipids
- High-density lipoprotein
- Triglyceride
- Body mass index
- Blood sugar
- Waist-to-height ratio
- Diabetes mellitus
- Enzyme
- Cancer
- White blood cell
- Cholesterol
- Blood cell
- Hyperuricemia
- Low-density lipoprotein
- Oxidase test

---
Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.