# Correlation vaginal microbiota and risk factor on pelvic organ prolapse
> Masrah W.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_105044461679
Jurnal / Konferensi: Hjog
Tahun terbit: 2026
DOI: https://doi.org/10.33574/hjog.0632
ISSN: 22419551
Kuartil SJR: Q4
Citations: 0

## Authors
- Masrah W.

## Abstract
Background: Pelvic organ prolapse (POP) is a common pelvic floor disorder that markedly affects women’s quality of life. Recent evidence suggests that vaginal microbiota imbalance may play a role in pelvic floor dysfunction; however, its association with POP risk factors remains poorly understood. Aim: This study aimed to evaluate the relationship between vaginal microbiota composition and clinical risk factors in women with pelvic organ prolapse. Method: A cross-sectional analytical study was conducted involving women diagnosed with POP and a comparison group without POP. Vaginal swab samples were analyzed to determine microbial composition at the phylum and genus levels. Result: Age above 60 years and menopausal duration of five years or more were significantly associated with increased POP risk. Bacillota was the predominant phylum in both groups, with higher proportions in the non-POP group. Women with POP showed greater microbial diversity and reduced protective bacterial profiles, indicating vaginal dysbiosis. Conclusion: Advanced age and prolonged menopause are key risk factors for POP and are associated with alterations in vaginal microbiota. These findings suggest that aging-related microbial shifts may contribute to POP development.

## Keywords
- Medicine
- Risk factor
- Vagina
- Menopause
- Gynecology
- Internal medicine
- Physiology
- Vaginal flora
- Pelvic floor
- Vaginal disease
- Obstetrics
- Epidemiology
- Lower risk
- Pelvic inflammatory disease
- Pelvic floor dysfunction

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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