# Analysis of quantitative electroencephalography in acute ischemic stroke with impaired cognitive function: a case control study
> Wafira N.U.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_105037816259
Jurnal / Konferensi: Gazzetta Medica Italiana Archivio Per Le Scienze Mediche
Tahun terbit: 2026
DOI: https://doi.org/10.23736/S0393-3660.25.05953-4
ISSN: 03933660
Kuartil SJR: Q4
Citations: 0

## Authors
- Wafira N.U.

## Abstract
BACKGROUND: Cognitive impairment following acute ischemic stroke significantly impacts patients’ quality of life and healthcare outcomes. Standard cognitive screening tools are often limited by stroke-induced disabilities. Quantitative electroencephalography (QEEG) offers an alternative for assessing brain wave activity linked to cognitive function.METHODS: This observational case-control study compared QEEG parameters (delta, theta, alpha, beta, delta-alpha ratio [DAR], and delta-theta-alpha-beta ratio [DTABR]) between acute ischemic stroke patients with and without cognitive impairment. Conducted at Dr. Wahidin Sudirohusodo General Hospital, the study included 40 patients with stroke onset ≤7 days, assessed using the Montreal Cognitive Assessment Indonesian version (MoCA-Ina). QEEG recordings were analyzed using Neuroguide Deluxe software, and statistical correlations between QEEG parameters and MoCA-Ina scores were evaluated.RESULTS: Patients with cognitive impairment demonstrated increased delta and theta wave activity, particularly in the frontal leads, compared to those without impairment. Slow-wave dominance (higher DAR and DTABR) was observed in impaired patients, correlating with reduced MoCA-Ina scores (delta: r=−0.563; theta: r=−0.387). Conversely, fast waves (alpha and beta) showed no significant differences between groups. Median DTABR values were significantly higher in the cognitive impairment group, reflecting greater structural and functional brain damage.CONCLUSIONS: Delta, theta, DAR, and DTABR parameters may serve as biomarkers for early detection of cognitive impairment in acute ischemic stroke. QEEG is proposed as a feasible screening tool to improve prognosis and management, with further research needed to explore its role in predicting long-term cognitive outcomes.

## Keywords
- Quantitative electroencephalography
- Cognition
- Electroencephalography
- Medicine
- Cognitive impairment
- Audiology
- Stroke (engine)
- Montreal Cognitive Assessment
- Observational study
- Elementary cognitive task
- Cardiology
- Case-control study
- Effects of sleep deprivation on cognitive performance
- Physical medicine and rehabilitation
- Internal medicine
- Neuroimaging
- Ischemic stroke
- Quality of life (healthcare)
- Physical therapy
- Cognitive test

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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