# Effectivity of carbazochrome addition in vitamin C and K combination in hemoptysis: a cohort-retrospective study
> Amahoru R.F.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_105033707261
Jurnal / Konferensi: Gazzetta Medica Italiana Archivio Per Le Scienze Mediche
Tahun terbit: 2026
DOI: https://doi.org/10.23736/S0393-3660.24.05838-8
ISSN: 03933660
Kuartil SJR: Q4
Citations: 0

## Authors
- Amahoru R.F.

## Abstract
BACKGROUND: Hemoptysis, caused by conditions like tuberculosis, lung cancer, and bronchiectasis, arises from the rupture of pulmonary vessels due to infection or inflammation. Carbazochrome, a hemostatic agent, helps reduce bleeding by stabilizing capillaries. Combining carbazochrome with vitamins C and K, which improve vascular integrity and promote coagulation, may enhance treatment effectiveness. This study aims to evaluate whether the combination of carbazochrome, vitamin C, and vitamin K provides better hemostatic control in hemoptysis patients than vitamins C and K alone.METHODS: A retrospective cohort study was conducted on 50 hemoptysis patients in Labuang Baji Hospital, Makassar, South Sulawesi, Indonesia. Data were collected by collecting medical record data.RESULTS: The study found a median patient age of 47, with most being male (57 patients) and having non-massive hemoptysis (82 patients). Carbazochrome was effective in all groups except those with MDR tuberculosis, bronchiectasis, and aspergilloma, significantly reducing hemoptysis duration (OR 10.92, p=0.00).CONCLUSIONS: The combination of carbazochrome, vitamin C, and vitamin K effectively shortens hemoptysis duration, especially in tuberculosis and lung cancer cases. By stabilizing capillaries, strengthening vessels, and enhancing coagulation, this synergistic approach accelerates bleeding cessation, offering a promising treatment for hemoptysis and improving outcomes.

## Keywords
- Medicine
- Vitamin C
- Gastroenterology
- Retrospective cohort study
- Surgery
- Medical record
- Vitamin
- Internal medicine
- Lung
- Lung cancer
- Combination therapy
- Tuberculosis
- Cohort
- Vitamin E
- Vitamin k
- Pharmacology
- Pulmonary tuberculosis

---
Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.