# The relationship between vitamin D levels and clinical symptoms and lesion size in chest radiographs of pulmonary tuberculosis in patients with comorbid diabetes mellitus
> Ramli A.N.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_105024552674
Jurnal / Konferensi: Italian Journal of Medicine
Tahun terbit: 2025
DOI: https://doi.org/10.4081/itjm.2025.2053
ISSN: 18779344
Kuartil SJR: Q4
Citations: 0

## Authors
- Ramli A.N.

## Abstract
Vitamin D acts as an immunomodulator, enhancing the body’s immune function. A deficiency of vitamin D in patients suffering from pulmonary tuberculosis (TB) along with diabetes mellitus (DM) can lead to increased morbidity and mortality from the disease. This study aimed to explore the link between vitamin D levels, clinical manifestations, and the extent of chest X-ray lesions in TB patients who also deal with DM. This research is a cross-sectional study that involves pulmonary TB patients with concurrent DM conditions conducted from September to October 2024. The study measured serum vitamin D levels, evaluated clinical symptoms, and assessed the extent of chest X-ray lesions. Data analysis was performed using Fisher’s exact test. The study included 40 individuals, with 60% aged between 41 and 59 years, and showed a 65% prevalence of vitamin D deficiency. A significant link was found between vitamin D deficiency and extensive lesions (p<0.05). Similarly, vitamin D deficiency was significantly correlated with the severity of symptoms (p<0.05). Vitamin D levels are related to the extent of lesions and clinical symptoms of pulmonary TB patients with comorbid DM.

## Keywords
- Medicine
- Diabetes mellitus
- Pulmonary tuberculosis
- vitamin D deficiency
- Internal medicine
- Vitamin D and neurology
- Lesion
- Tuberculosis
- Type 2 Diabetes Mellitus
- Gastroenterology
- Vitamin
- Radiography
- Immune system
- Complication
- Surgery
- Cross-sectional study

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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