Utilization of Corn Silk as Anti-Inflammatory and Wound Healing Ointment

Abstract

Postoperative wound care generally uses synthetic drugs that can cause antibiotic resistance, so a safer and more effective alternative is needed.Corn hair (Zea mays L.) is an abundant waste and rich in phenolic compounds that have anti-inflammatory and wound healing activities.This study aims to develop and evaluate ointment from corn hair extract as an anti-inflammatory and wound-healing agent.Corn hair extract ointment concentrations of 5, 7, and 9% were tested in vivo using a cut wound model in mice (Mus musculus) to determine the wound healing process.In addition, hematology tests and histopathology tests of mice were conducted to see the healing response of corn hair ointment.Data were analyzed using One Way ANOVA with the IBM SPSS® 25 program.The test results showed that corn hair extract ointment with a concentration of 7% has great potential as an effective and safe natural alternative for postoperative wound care, with significant anti-inflammatory and wound healing abilities.

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