# Comparative sequences of two type 1 dengue virus strains possessing different growth characteristics in vitro
> Ishak H.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_0035059088
Jurnal / Konferensi: Microbiology and Immunology
Tahun terbit: 2001
DOI: https://doi.org/10.1111/j.1348-0421.2001.tb02627.x
ISSN: 03855600
Kuartil SJR: Q3
Citations: 26

## Authors
- Ishak H.

## Abstract
The complete genome sequences of two dengue-1 virus strains having different growth characteristics (Mochizuki and A88) were compared with other published strains. The sequence analysis indicated several unique amino acid changes throughout the coding region of Mochizuki strain, mostly in envelope (E) protein. A unique amino acid, Ile-69 for Mochizuki strain at E protein resulted in the loss of an Asn-67-linked glycosylation site. A Thr substitution for Ala-114 at C protein and amino acid changes found in E, non-structural NS3, NS4a, and NS5 proteins were unique for A88 strain. These substitutions might be correlated to their different growth characteristics in vitro.

## Keywords
- Biology
- Dengue virus
- Strain (injury)
- In vitro
- Amino acid
- Glycosylation
- Peptide sequence
- Dengue fever
- Virology
- Virus
- Microbiology
- Genetics
- Gene
- Anatomy

---
Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.