# Improvements in appetite and growth in helminth-infected schoolboys three and seven weeks after a single dose of pyrantel pamoate
> Hadju V.

URL kanonis: https://discover.unhas.ac.id/publications/pub_scopus_0029959487
Jurnal / Konferensi: Parasitology
Tahun terbit: 1996
DOI: https://doi.org/10.1017/s0031182000081579
ISSN: 00311820
Kuartil SJR: Q1
Citations: 56

## Authors
- Hadju V.

## Abstract
Appetite and growth were studied in primary schoolboys (6-10 years) infected with Ascaris lumbricoides (86%) and Trichuris trichiura (100%) who received a single dose of pyrantel pamoate (which has little or no effect on Trichuris trichiura) or a placebo. Boys were examined, allocated at random by descending Ascaris egg count to pyrantel (PR, n = 36) or placebo (PL, n = 36) groups, treated, and re-examined 3 and 7 weeks later. The 2 groups did not differ significantly before treatment in helminth infections, appetite, or growth. Three and 7 weeks after treatment, the PR group exhibited significantly greater increases than did the PL group in weight (0.2 kg and 0.4 kg more, respectively) and percentage weight-for-age (0.6% and 1.7% points more, respectively). Appetite increased significantly in the PR group at 3 and 7 weeks (P < 0.0005 and P < 0.01, respectively) but not in the PL group. The prevalence and intensity of A. lumbricoides infection were greatly reduced in the PR group at 3 and 7 weeks (both P < 0.0001) but not in the PL group. We conclude that treatment with pyrantel pamoate may improve appetite and growth in school children in areas where A. lumbricoides infections and poor growth are highly prevalent.

## Keywords
- Pyrantel
- Biology
- Helminths
- Appetite
- Helminthiasis
- Anthelmintic
- Physiology
- Immunology
- Pharmacology
- Internal medicine
- Veterinary medicine
- Zoology
- Endocrinology
- Medicine

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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