# Prolongation of QTC interval associated with drugs used in management of COVID 19
> Amir M.

URL kanonis: https://discover.unhas.ac.id/publications/prolongation-of-qtc-interval-associated-with-drugs-used-in-management-of-covid-1
Jurnal / Konferensi: International Journal of Pharmaceutical Research
Tahun terbit: 2020
DOI: https://doi.org/10.31838/ijpr/2020.12.04.504
ISSN: 09752366
Citations: 0

## Authors
- Amir M.

## Abstract
The recent outbreak of the novel coronavirus officially known as Severe Acute Respiratory SyndromeCoronavirus-2 (SARS-CoV-2) has progressed into a global pandemic The United States Food and Drug Administration (FDA) issued an emergency use authorization (EUA) for several established antimicrobials and investigational ones However, further observations on patients receiving these drugs showed severe drugdrug interaction leading to potentially life-threatening arrhythmias Corrected QT interval prolongation has been known as a resulting side effect of individual microbial drugs or interactions between several concomitantly used drugs, with resulting life-threatening arrhythmias Furthermore, arrhythmic complication of COVID-19 oftenly necessitates the use of antiarrhythmic drugs, further increasing the risk of potential severe drug-drug interactions This review aims to present current data concerning QT-prolonging risk of several drug used in the management of COVID-19 and potential drug-drug interactions between them

## Keywords
- Prolongation
- QT interval
- Coronavirus disease 2019 (COVID-19)
- Medicine
- Interval (graph theory)
- 2019-20 coronavirus outbreak
- Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)
- Long QT syndrome
- Torsades de pointes
- Internal medicine
- Cardiology
- Virology
- Mathematics
- Combinatorics
- Infectious disease (medical specialty)
- Disease
- Outbreak

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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