Potential of Isothiocyanates from Moringa as Antiobesity: A Review

Abstract

Phytotherapy is one example of an alternative therapy that is thought to help individuals with chronic non-communicable illnesses. Moringa oleifera (Mo) is now being investigated in this area for its total phenolic content and nutritional benefits. In addition to phenolic chemicals, there is a lot of interest in the phytochemical makeup. The presence of isothiocyanates and glucosinolates characterizes this composition. The extra sugar in the isothiocyanates produced by the biotransformation of Moringa glucosinolates gives these bioactive chemicals stability over other isothiocyanates derived from other crops. Isothiocyanates have been reported to be effective in preventing and improving some chronic diseases such as obesity which has a fairly high prevalence. Separation of Isothiocyanate compounds in Moringa tissue can be improved by certain separation techniques, which are modified. This review aims to highlight certain separation techniques and study the properties and potential use of Moringa isothiocyanate (MITC) as a drug against obesity through various methods. MITC compound found in Moringa extract can reduce liver fat accumulation, body weight, fat weight, and fat tissue estimation. In addition, MITC can increase HDL levels while decreasing TC, TG, LDL, and VLDL. In addition, leptin, vaspin, and resistin levels were all decreased by MITC. 

Access to Document

Other files and links

• Link to publication in Scopus
• Open Access Version Available

Fingerprint