# Phytochemical Profile and Biological Activities of Ethylacetate Extract of Peanut (Arachis hypogaea L.) Stems: In-Vitro and In-Silico Studies with Bibliometric Analysis
> Sahidin I.

URL kanonis: https://discover.unhas.ac.id/publications/phytochemical-profile-and-biological-activities-of-ethylacetate-extract-of-peanu
Jurnal / Konferensi: Indonesian Journal of Science and Technology
Tahun terbit: 2023
DOI: https://doi.org/10.17509/ijost.v8i2.54822
ISSN: 25281410
Kuartil SJR: Q1
Citations: 68

## Authors
- Sahidin I.

## Abstract
The utilization of the stems, leaves, and hulls of peanuts (Arachis hypogea) is not as popular as the seeds. This study aimed to investigate the chemical contents and pharmacological activities of A. hypogaea stems in-vitro and in-silico. This study was also completed with bibliometric analysis. The methanol extract (ME) was reextracted by ethylacetate to get ethyl acetate extract (EAE). The chemical contents of EAE were analyzed by phytochemical screening, Liquid Chromatography-Mass Spectroscopy (LC-MS/MS), TPC (Total Phenolic Content), and TFC (Total Flavonoid Content). In-vitro and in-silico studies evaluated antioxidant potency, toxicity, and cytotoxicity toward MCF-7 cell lines. The results showed that EAE contained terpenoids, flavonoids, alkaloids, and phenolics which were supported by LC-MS/MS data. The EAE was categorized as a very strong antioxidant and moderately active in both cytotoxicity and toxicity.

## Keywords
- Phytochemical
- Arachis hypogaea
- Chemistry
- Terpenoid
- In silico
- Flavonoid
- Antioxidant
- Ethyl acetate
- Traditional medicine
- Cytotoxicity
- In vitro
- Botany
- Biology
- Chromatography
- Biochemistry
- Medicine
- Gene

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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