Share
Export Citation
Okra powder effect to low density lipoprotein and triglycerides in diabetic Wistar rat
Arwini A.
ACM International Conference Proceeding Series
Abstract
This study aimed to find out the effect of okra powder treatment on the changes of the concentration of the low density of lipoprotein (LDL) and triglycerides in diabetic Wistar rats. The research was an experimental research with the re-post test control group design. The research subjects were 15 furrow Wistar rats. The experiment animals were made diabetes by injecting alloxan 140 mg/kg. The subjects were divided into three groups: group 1 (moderate dosage o 100 mg/kg), group 2 (high dosage of 200 mg/kg), and group 3 (control). The intervention was administered in 14 days. The data analysis used the paired T-test to test the subjects before and after the treatment, and the One• Way ANOVA test was used to test the difference between the groups. The research results indicated that the treatment with okra powder had a significant effect on the concentration of LDL in group 1 (from 38.60 ± 6.693 to 24.80 ± 2.864, p=0.005) and in group 2 (from 39.00 ± 7.483 to 24.80 ± 2.490, p=0.004); on the other hand, there happened a significant increase in control group (from 42.20 ± 3.347 to 71.40 ± 1.817, p=0.000). The research result of triglycerides concentration indicated a significant effect before and after the treatment with okra powder in group 1 (from 125.40 ± 13.6 to 53.20 ± 24.056, p=0.000) and in group 2 (126.80 ± 14.20 to 49.20 ± 11.735, p=0.000), and in control group experienced an increase though not significant (from 127.80 ± 18.53 to 163.20 ± 29.141, p=0.028). The post hoc analysis indicated an effect of the moderate dosage decrease, and the high dosage of LDL did not show a significant difference of LDL (p=0.800) nor did the high dosage of triglycerides (p=0.864). Thus the okra powder could reduce LDL and triglycerides in diabetes Wistar rats.