# Novel Complex of Zinc (II) Dichloroethylenediamine: Synthesis, Characterization, In-silico, and In-vitro Evaluation against Cervical Cancer Cells
> Raya I.

URL kanonis: https://discover.unhas.ac.id/publications/novel-complex-of-zinc-ii-dichloroethylenediamine-synthesis-characterization-in-s
Jurnal / Konferensi: Asian Pacific Journal of Cancer Prevention
Tahun terbit: 2023
DOI: https://doi.org/10.31557/APJCP.2023.24.12.4155
ISSN: 15137368
Kuartil SJR: Q2
Citations: 2

## Authors
- Raya I.

## Abstract
The observed data indicated that the Zn(en)Cl2 complex bound to DNA at the nitrogenous base Guanine (DG) by coordinate covalent bonds. Interestingly, DG maintained interaction with the complex until the end of the docking simulation. Additionally, molecular dynamics (MD) simulation was conducted, and the results showed that Zn(en)Cl2 remained bound to the DNA binding pocket all through the process.

## Keywords
- HeLa
- Chemistry
- Zinc
- Guanine
- In silico
- DNA
- In vitro
- Docking (animal)
- Cancer cell
- Stereochemistry
- Combinatorial chemistry
- Biochemistry
- Cancer
- Biology
- Nucleotide
- Medicine
- Organic chemistry
- Gene
- Genetics
- Nursing

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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