# Neutrophil-Lymphocyte Ratio and Procalcitonin as Predictors of the Severity of Acute Pancreatitis
> Iriana D.

URL kanonis: https://discover.unhas.ac.id/publications/neutrophil-lymphocyte-ratio-and-procalcitonin-as-predictors-of-the-severity-of-a
Jurnal / Konferensi: Indonesian Journal of Clinical Pathology and Medical Laboratory
Tahun terbit: 2021
DOI: https://doi.org/10.24293/ijcpml.v28i1.1699
ISSN: 24774685
Kuartil SJR: Q4
Citations: 0

## Authors
- Iriana D.

## Abstract
The Neutrophil-Lymphocyte Ratio (NLR) and procalcitonin are used to indicate systemic inflammation in variousmedical disorders. Both parameters were determined in this study to predict the severity of acute pancreatitis. This studywas a cross-sectional study using a retrospective approach to patients diagnosed with acute pancreatitis by using medicalrecord data from patients at Dr. Wahidin Sudirohusoso Hospital, Makassar, from January 2014 to May 2019. This studycomprised 35 patients hospitalized with acute pancreatitis, with a similar proportion of males and females. This studydiscovered that the mean age in this study was 44.17±12.9 years. The most prevalent cause was Gallstones (77.1%), themost severe degree was mild (54.2%), and the highest outcome was survival (77.1%). The NLR (9.93±11.19, p=0.011)increased in proportion to severity. However, additional analysis based on classification of disease severity revealed thatonly mild-severe NLR was significant (p=0.005). Procalcitonin (8.13±11.25, p=0.001) increased along with the increaseddisease severity, and the subsequent analysis showed that the distribution of severity was similar. The NLR can predict theseverity of acute pancreatitis but is less effective than procalcitonin. This study required a more proportional subjectpopulation and consideration of other factors.

## Keywords
- Procalcitonin
- Medicine
- Acute pancreatitis
- Internal medicine
- Gastroenterology
- Pancreatitis
- Neutrophil to lymphocyte ratio
- APACHE II
- Lymphocyte
- Gallstones
- Retrospective cohort study
- Severity of illness
- Intensive care unit
- Sepsis

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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