# Need of booster vaccine doses to counteract the emergence of SARS-CoV-2 variants in the context of the Omicron variant and increasing COVID-19 cases: An update > Mohapatra R.K. URL kanonis: https://discover.unhas.ac.id/publications/need-of-booster-vaccine-doses-to-counteract-the-emergence-of-sars-cov-2-variants Jurnal / Konferensi: Human Vaccines and Immunotherapeutics Tahun terbit: 2022 DOI: https://doi.org/10.1080/21645515.2022.2065824 ISSN: 21645515 Kuartil SJR: Q2 Citations: 25 ## Authors - Mohapatra R.K. ## Abstract The emergence of different variants of SARS-CoV-2, including the Omicron (B.1.1.529) variant in November 2021, has resulted in a continuous major health concern at a global scale. Presently, the Omicron variant has spread very rapidly worldwide within a short time period. As the most mutated variant of SARS-CoV-2, Omicron has instilled serious uncertainties on the effectiveness of humoral adaptive immunity generated by COVID-19 vaccination or an active viral infection as well as the protection provided by antibody-based immunotherapies. Amidst such high public health concerns, the need to carry out booster vaccination has been emphasized. Current evidence reveals the importance of incorporating booster vaccination using several vaccine platforms, such as viral vector- and mRNA-based vaccines, as well as other platforms that are under explorative investigations. Further research is being conducted to assess the effectiveness and durability of protection provided by booster COVID-19 vaccination against Omicron and other SARS-CoV-2 variants. ## Keywords - Booster (rocketry) - Vaccination - Coronavirus disease 2019 (COVID-19) - Virology - Context (archaeology) - Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) - Immunity - Pandemic - Immunology - Medicine - Biology - Immune system - Infectious disease (medical specialty) - Disease - Physics - Astronomy - Pathology - Paleontology --- Sumber: Discover Unhas — RIMS Universitas Hasanuddin. Saat mengutip, gunakan DOI bila tersedia atau URL kanonis di atas.