# Molecular characterisation of mutations associated with resistance to first- and second-line drugs among Indonesian patients with tuberculosis
> Umar F.F.

URL kanonis: https://discover.unhas.ac.id/publications/molecular-characterisation-of-mutations-associated-with-resistance-to-first-and
Jurnal / Konferensi: Journal of Taibah University Medical Sciences
Tahun terbit: 2020
DOI: https://doi.org/10.1016/j.jtumed.2019.12.003
ISSN: 16583612
Kuartil SJR: Q3
Citations: 13

## Authors
- Umar F.F.

## Abstract
Of the 50 strains analysed, most of the mutations in the <i>rpoB</i> gene associated with rifampicin-resistance were also detected in the <i>katG</i> and <i>gyrA</i> genes. Molecular characterisation using DNA sequencing techniques is a highly sensitive approach for detecting mutations.

## Keywords
- rpoB
- Mycobacterium tuberculosis
- Capreomycin
- Rifampicin
- Isoniazid
- Tuberculosis
- Biology
- Genetics
- Gene mutation
- Mutation
- Streptomycin
- Gene
- Drug resistance
- Virology
- Microbiology
- Medicine
- Antibiotics
- Ethambutol
- Pathology
- 16S ribosomal RNA

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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