# Exploring the Cytotoxic Activity of Dillenia serrata Thunb. Leaf Extracts: An In Vitro and In Silico Investigation
> Rasyid H.

URL kanonis: https://discover.unhas.ac.id/publications/exploring-the-cytotoxic-activity-of-dillenia-serrata-thunb-leaf-extracts-an-in-v
Jurnal / Konferensi: Asian Pacific Journal of Cancer Prevention
Tahun terbit: 2025
DOI: https://doi.org/10.31557/APJCP.2025.26.3.1043
ISSN: 15137368
Kuartil SJR: Q2
Citations: 1

## Authors
- Rasyid H.

## Abstract
All extracts demonstrated intense toxicity levels. Out of all the extracts, ethyl acetate extract exhibited the strongest cytotoxic properties to HeLa cell lines with IC50 value 91.08±0.23 μg/mL. Ethyl acetate extract of D. serrata T. contains Phytol compounds which have a quite good affinity to the EGFR. According to this study, ethyl acetate extract has the potential to be used as an alternative to anticancer medication.

## Keywords
- In silico
- In vitro
- Traditional medicine
- Biology
- Botany
- Chemistry
- Biochemistry
- Medicine
- Gene

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Sumber: Discover Unhas — RIMS Universitas Hasanuddin.
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